FUNDING CANCER - Enhancing Mechanistic Research on Precision Probiotic Therapies
Sponsor: NIH
Description: The purpose of this NOFO is to support highly innovative mechanistic research to accelerate the development of effective precision probiotic interventions. Applicants should aim to identify, understand, and develop strategies to address barriers in precision probiotic interventions' development to account for human heterogeneity resulting in inconsistent responses to probiotic treatments. The first phase, funded by the R61 mechanism, will provide up to two years of support to identify host biological patterns that are correlated with differences in probiotic clinical effects using observational or secondary data analysis studies. The second phase, funded by the R33 mechanism, will support studies to assess the causality of the factors identified in the R61 phase that impact probiotic responsiveness through rigorous mechanistic study designs in animal models or human subjects.
- Applications Due:
- June 2, 2025
- February 2, 2026
- October 1, 2026
- June 2, 2027
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